Cargando…

Preferential Localization of Human Origins of DNA Replication at the 5′-Ends of Expressed Genes and at Evolutionarily Conserved DNA Sequences

BACKGROUND: Replication of mammalian genomes requires the activation of thousands of origins which are both spatially and temporally regulated by as yet unknown mechanisms. At the most fundamental level, our knowledge about the distribution pattern of origins in each of the chromosomes, among differ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Valenzuela, Manuel S., Chen, Yidong, Davis, Sean, Yang, Fan, Walker, Robert L., Bilke, Sven, Lueders, John, Martin, Melvenia M., Aladjem, Mirit I., Massion, Pierre P., Meltzer, Paul S.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094316/ https://www.ncbi.nlm.nih.gov/pubmed/21602917 http://dx.doi.org/10.1371/journal.pone.0017308

Ejemplares similares

A chromatin structure‐based model accurately predicts DNA replication timing in human cells
por: Gindin, Yevgeniy, et al.
Publicado: (2014)

DNA replication profiling by molecular combing on single DNA fibers
por: Fu, Haiqing, et al.
Publicado: (2022)

Methylation of Histone H3 on Lysine 79 Associates with a Group of Replication Origins and Helps Limit DNA Replication Once per Cell Cycle
por: Fu, Haiqing, et al.
Publicado: (2013)

Correction: Methylation of Histone H3 on Lysine 79 Associates with a Group of Replication Origins and Helps Limit DNA Replication Once per Cell Cycle
por: Fu, Haiqing, et al.
Publicado: (2013)

Allele-specific analysis of DNA replication origins in mammalian cells
por: Bartholdy, Boris, et al.
Publicado: (2015)

The DNA repair endonuclease Mus81 facilitates fast DNA replication in the absence of exogenous damage
por: Fu, Haiqing, et al.
Publicado: (2015)

Replicon: a software to accurately predict DNA replication timing in metazoan cells
por: Gindin, Yevgeniy, et al.
Publicado: (2014)

Initiation of DNA replication at the human β-globin 3′ enhancer
por: Buzina, Alla, et al.
Publicado: (2005)

ATAD5 regulates the lifespan of DNA replication factories by modulating PCNA level on the chromatin
por: Lee, Kyoo-young, et al.
Publicado: (2013)

Chromatin-Bound Cullin-Ring Ligases: Regulatory Roles in DNA Replication and Potential Targeting for Cancer Therapy
por: Jang, Sang-Min, et al.
Publicado: (2018)

The Major Roles of DNA Polymerases Epsilon and Delta at the Eukaryotic Replication Fork Are Evolutionarily Conserved
por: Miyabe, Izumi, et al.
Publicado: (2011)

Distinct epigenetic features of differentiation-regulated replication origins
por: Smith, Owen K., et al.
Publicado: (2016)

Mus81-mediated DNA cleavage resolves replication forks stalled by topoisomerase I–DNA complexes
por: Regairaz, Marie, et al.
Publicado: (2011)

SIRT1 Deacetylates TopBP1 and Modulates Intra-S-Phase Checkpoint and DNA Replication Origin Firing
por: Wang, Rui-Hong, et al.
Publicado: (2014)

Ribosomal DNA harbors an evolutionarily conserved clock of biological aging
por: Wang, Meng, et al.
Publicado: (2019)

Extra View: Sirt1 Acts As A Gatekeeper Of Replication Initiation To Preserve Genomic Stability.
por: Utani, Koichi, et al.
Publicado: (2018)

Protection of CpG islands from DNA methylation is DNA-encoded and evolutionarily conserved
por: Long, Hannah K., et al.
Publicado: (2016)

SIRT1/PARP1 crosstalk: connecting DNA damage and metabolism
por: Luna, Augustin, et al.
Publicado: (2013)

SIRT1 Prevents R-Loops during Chronological Aging by Modulating DNA Replication at rDNA Loci
por: Thakur, Bhushan L., et al.
Publicado: (2023)

Allele-Specific Genome-wide Profiling in Human Primary Erythroblasts Reveal Replication Program Organization
por: Mukhopadhyay, Rituparna, et al.
Publicado: (2014)

Ageing European lobsters (Homarus gammarus) using DNA methylation of evolutionarily conserved ribosomal DNA
por: Fairfield, Eleanor A., et al.
Publicado: (2021)

Phosphorylated SIRT1 associates with replication origins to prevent excess replication initiation and preserve genomic stability
por: Utani, Koichi, et al.
Publicado: (2017)

The DNA binding and 3′-end preferential activity of human tyrosyl-DNA phosphodiesterase
por: Dexheimer, Thomas S., et al.
Publicado: (2010)

Origins of DNA replication
por: Ekundayo, Babatunde, et al.
Publicado: (2019)

Identification of evolutionarily conserved DNA damage response genes that alter sensitivity to cisplatin
por: Gaponova, Anna V., et al.
Publicado: (2016)

Preferential expression of scores of functionally and evolutionarily diverse DNA and RNA-binding proteins during Oxytricha trifallax macronuclear development
por: Neeb, Zachary T., et al.
Publicado: (2017)

Replication of alpha-satellite DNA arrays in endogenous human centromeric regions and in human artificial chromosome
por: Erliandri, Indri, et al.
Publicado: (2014)

A predictable conserved DNA base composition signature defines human core DNA replication origins
por: Akerman, Ildem, et al.
Publicado: (2020)

Analysis of the DNA-binding properties of Alx1, an evolutionarily conserved regulator of skeletogenesis in echinoderms
por: Guerrero-Santoro, Jennifer, et al.
Publicado: (2021)

Evidence for a Functional Link between Chromosomal Breakpoints and Aberrant DNA Methylation in Cancer
por: Bilke, Sven, et al.
Publicado: (2014)

Predicted Functions of MdmX in Fine-Tuning the Response of p53 to DNA Damage
por: Kim, Sohyoung, et al.
Publicado: (2010)

Predicted Role of NAD Utilization in the Control of Circadian Rhythms during DNA Damage Response
por: Luna, Augustin, et al.
Publicado: (2015)

A replicator-specific binding protein essential for site-specific initiation of DNA replication in mammalian cells
por: Zhang, Ya, et al.
Publicado: (2016)

DNA replication origins in archaea
por: Wu, Zhenfang, et al.
Publicado: (2014)

Correction: Origins of DNA replication
Publicado: (2019)

Dynamics of replication origin over-activation
por: Fu, Haiqing, et al.
Publicado: (2021)

Interactions of MCP1 with Components of the Replication Machinery in Mammalian Cells
por: Bronze-da-Rocha, Elsa, et al.
Publicado: (2011)

An evolutionarily conserved stop codon enrichment at the 5′ ends of mammalian piRNAs
por: Bornelöv, Susanne, et al.
Publicado: (2022)

The eukaryotic MEP-pathway genes are evolutionarily conserved and originated from Chlaymidia and cyanobacteria
por: Zeng, Liping, et al.
Publicado: (2021)

G-Quadruplex DNA Sequences Are Evolutionarily Conserved and Associated with Distinct Genomic Features in Saccharomyces cerevisiae
por: Capra, John A., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_t8rs00fuvc6uith2jst4ppgpvg