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VEGF attenuates development from cardiac hypertrophy to heart failure after aortic stenosis through mitochondrial mediated apoptosis and cardiomyocyte proliferation

BACKGROUND: Aortic stenosis (AS) affects 3 percent of persons older than 65 years and leads to greater morbidity and mortality than other cardiac valve diseases. Surgery with aortic valve replacement (AVR) for severe symptomatic AS is currently the only treatment option. Unfortunately, in patients w...

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Detalles Bibliográficos
Autores principales: Xu, Xiao H, Xu, Jing, Xue, Lei, Cao, Hai L, Liu, Xiang, Chen, Yi J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094376/
https://www.ncbi.nlm.nih.gov/pubmed/21496294
http://dx.doi.org/10.1186/1749-8090-6-54