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Sensory-motor deficits and neurofilament disorganization in gigaxonin-null mice
BACKGROUND: Giant Axonal Neuropathy (GAN) is a fatal neurodegenerative disorder with early onset characterized by a severe deterioration of the peripheral and central nervous system, involving both the motor and the sensory tracts and leading to ataxia, speech defect and intellectual disabilities. T...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094382/ https://www.ncbi.nlm.nih.gov/pubmed/21486449 http://dx.doi.org/10.1186/1750-1326-6-25 |