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Dysregulation of IFN System Can Lead to Poor Response to Pegylated Interferon and Ribavirin Therapy in Chronic Hepatitis C

BACKGROUND: Despite being expensive, the standard combination of pegylated interferon (Peg-IFN)- α and ribavirin used to treat chronic hepatitis C (CH) results in a moderate clearance rate and a plethora of side effects. This makes it necessary to predict patient outcome so as to improve the accurac...

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Detalles Bibliográficos
Autores principales: Onomoto, Koji, Morimoto, Shiho, Kawaguchi, Takahisa, Toyoda, Hidenori, Tanaka, Masami, Kuroda, Masahiko, Uno, Kazuko, Kumada, Takashi, Matsuda, Fumihiko, Shimotohno, Kunitada, Fujita, Takashi, Murakami, Yoshiki
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094385/
https://www.ncbi.nlm.nih.gov/pubmed/21603632
http://dx.doi.org/10.1371/journal.pone.0019799