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Frequency analysis of TRBV subfamily sjTRECs to characterize T-cell reconstitution in acute leukemia patients after allogeneic hematopoietic stem cell transplantation

BACKGROUND: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) leads to a prolonged state of immunodeficiency and requires reconstitution of normal T-cell immunity. Signal joint T-cell receptor excision DNA circles (sjTRECs) are markers of developmental proximity to the thymus that have...

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Detalles Bibliográficos
Autores principales: Wu, Xiuli, Zhu, Kanger, Du, Xin, Chen, Shaohua, Yang, Lijian, Wu, Jufeng, Liu, Qifa, Li, Yangqiu
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094391/
https://www.ncbi.nlm.nih.gov/pubmed/21513557
http://dx.doi.org/10.1186/1756-8722-4-19