Development of an MHC class I L(d)-restricted PSA peptide-loaded tetramer for detection of PSA-specific CD8(+) T cells in the mouse

OBJECTIVES: We set out to develop a prostate specific antigen (PSA) peptide-loaded tetramer for enumeration of PSA-specific CD8(+) T cells in the Balb/c mouse model. METHODS: A candidate MHC class I PSA peptide (HPQKVTKFML(188–197)) was selected based on its ability to restimulate PSA-specific CD8(+...

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Detalles Bibliográficos
Autores principales: Lemke, Caitlin D., Graham, Jessica B., Lubaroff, David M., Salem, Aliasger K.
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094480/
https://www.ncbi.nlm.nih.gov/pubmed/21263453
http://dx.doi.org/10.1038/pcan.2010.57

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094480/
https://www.ncbi.nlm.nih.gov/pubmed/21263453
http://dx.doi.org/10.1038/pcan.2010.57

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