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Absence of association of a single-nucleotide polymorphism in the TERT-CLPTM1L locus with age-related phenotypes in a large multicohort study: the HALCyon programme

Several age-related traits are associated with shorter telomeres, the structures that cap the end of linear chromosomes. A common polymorphism near the telomere maintenance gene TERT has been associated with several cancers, but relationships with other aging traits such as physical capability have...

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Detalles Bibliográficos
Autores principales: Alfred, Tamuno, Ben-Shlomo, Yoav, Cooper, Rachel, Hardy, Rebecca, Cooper, Cyrus, Deary, Ian J, Elliott, Jane, Gunnell, David, Harris, Sarah E, Kivimaki, Mika, Kumari, Meena, Martin, Richard M, Power, Chris, Sayer, Avan Aihie, Starr, John M, Kuh, Diana, Day, Ian N M
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094481/
https://www.ncbi.nlm.nih.gov/pubmed/21332924
http://dx.doi.org/10.1111/j.1474-9726.2011.00687.x