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Impairment of endothelial progenitor cell function and vascularization capacity by aldosterone in mice and humans

AIMS: Hyperaldosteronism is associated with vascular injury and increased cardiovascular events. Bone marrow-derived endothelial progenitor cells (EPCs) play an important role in endothelial repair and vascular homeostasis. We hypothesized that hyperaldosteronism impairs EPC function and vasculariza...

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Detalles Bibliográficos
Autores principales: Thum, Thomas, Schmitter, Kerstin, Fleissner, Felix, Wiebking, Volker, Dietrich, Bernd, Widder, Julian D., Jazbutyte, Virginija, Hahner, Stefanie, Ertl, Georg, Bauersachs, Johann
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094546/
https://www.ncbi.nlm.nih.gov/pubmed/20926363
http://dx.doi.org/10.1093/eurheartj/ehq254