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Nanoprodrugs of NSAIDs: Preparation and Characterization of Flufenamic Acid Nanoprodrugs

We demonstrated that hydrophobic derivatives of the nonsteroidal anti-inflammatory drug (NSAID)flufenamic acid (FA), can be formed into stable nanometer-sized prodrugs (nanoprodrugs) that inhibit the growth of glioma cells, suggesting their potential application as anticancer agent. We synthesized h...

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Detalles Bibliográficos
Autores principales: Lee, Bong-Seop, Yoon, Chi Woo, Osipov, Arsen, Moghavem, Nuriel, Nwachokor, Daniel, Amatya, Rina, Na, Rebekah, Pantoja, Joe L., Pham, Michael D., Black, Keith L., Yu, John S.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095474/
https://www.ncbi.nlm.nih.gov/pubmed/21603162
http://dx.doi.org/10.1155/2011/980720