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Naturally Occurring Osmolyte, Trehalose Induces Functional Conformation in an Intrinsically Disordered Activation Domain of Glucocorticoid Receptor

Intrinsically disordered (ID) regions are frequently found in the activation domains of many transcription factors including nuclear hormone receptors. It is believed that these ID regions promote molecular recognition by creating large surfaces suitable for interactions with their specific protein...

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Detalles Bibliográficos
Autores principales: Khan, Shagufta H., Arnott, John A., Kumar, Raj
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095608/
https://www.ncbi.nlm.nih.gov/pubmed/21603604
http://dx.doi.org/10.1371/journal.pone.0019689