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Invariant NKT Cell Lines Derived from the NOD·H2(h4) Mouse Enhance Autoimmune Thyroiditis

To study the role of invariant Natural Killer T cell ( iNKT) cells in autoimmune thyroiditis, we derived two iNKT cell lines from the spleens of NOD· H2(h4) mice, a strain that develops spontaneous autoimmune thyroiditis exacerbated by excess dietary iodine. The two lines were CD1d-restricted and ex...

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Detalles Bibliográficos
Autores principales: Sharma, Rajni B., Fan, Xiaoguang, Caturegli, Patrizio, Rose, Noel R., Burek, C. Lynne
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095906/
https://www.ncbi.nlm.nih.gov/pubmed/21603172
http://dx.doi.org/10.4061/2011/895923