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First report of molecular detection of fluoroquinolone resistance-associated gyrA mutations in multidrug-resistant clinical Mycobacterium tuberculosis isolates in Kuwait

BACKGROUND: Nearly 5% of all Mycobacterium tuberculosis strains worldwide are resistant at least to rifampicin and isoniazid (multidrug-resistant tuberculosis, MDR-TB). Inclusion of a fluoroquinolone and an injectable agent (kanamycin, amikacin or capreomycin) in multidrug therapy is crucial for pro...

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Detalles Bibliográficos
Autores principales: Al-Mutairi, Noura M, Ahmad, Suhail, Mokaddas, Eiman
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095995/
https://www.ncbi.nlm.nih.gov/pubmed/21492420
http://dx.doi.org/10.1186/1756-0500-4-123