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Pro-inflammatory endothelial cell dysfunction is associated with intersectin-1s down-regulation

BACKGROUND: The response of lung microvascular endothelial cells (ECs) to lipopolysaccharide (LPS) is central to the pathogenesis of lung injury. It is dual in nature, with one facet that is pro-inflammatory and another that is cyto-protective. In previous work, overexpression of the anti-apoptotic...

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Detalles Bibliográficos
Autores principales: Singla, Sunit, Predescu, Dan, Bardita, Cristina, Wang, Minhua, Zhang, Jian, Balk, Robert A, Predescu, Sanda
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096597/
https://www.ncbi.nlm.nih.gov/pubmed/21486462
http://dx.doi.org/10.1186/1465-9921-12-46