AAV2-Mediated Subretinal Gene Transfer of hIFN-α Attenuates Experimental Autoimmune Uveoretinitis in Mice

BACKGROUND: Recent reports show that gene therapy may provide a long-term, safe and effective intervention for human diseases. In this study, we investigated the effectiveness of adeno-associated virus 2 (AAV2) based human interferon-alpha (hIFN-α) gene therapy in experimental autoimmune uveoretinit...

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Detalles Bibliográficos
Autores principales: Tian, Lichun, Yang, Peizeng, Lei, Bo, Shao, Ju, Wang, Chaokui, Xiang, Qin, Wei, Lin, Peng, Zhougui, Kijlstra, Aize
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096632/
https://www.ncbi.nlm.nih.gov/pubmed/21611186
http://dx.doi.org/10.1371/journal.pone.0019542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096632/
https://www.ncbi.nlm.nih.gov/pubmed/21611186
http://dx.doi.org/10.1371/journal.pone.0019542

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