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An shRNA-Based Screen of Splicing Regulators Identifies SFRS3 as a Negative Regulator of IL-1β Secretion

The generation of diversity and plasticity of transcriptional programs are key components of effective vertebrate immune responses. The role of Alternative Splicing has been recognized, but it is underappreciated and poorly understood as a critical mechanism for the regulation and fine-tuning of phy...

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Detalles Bibliográficos
Autores principales: Moura-Alves, Pedro, Neves-Costa, Ana, Raquel, Helena, Pacheco, Teresa Raquel, D'Almeida, Bruno, Rodrigues, Raquel, Cadima-Couto, Iris, Chora, Ângelo, Oliveira, Mariana, Gama-Carvalho, Margarida, Hacohen, Nir, Moita, Luis F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096647/
https://www.ncbi.nlm.nih.gov/pubmed/21611201
http://dx.doi.org/10.1371/journal.pone.0019829