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An shRNA-Based Screen of Splicing Regulators Identifies SFRS3 as a Negative Regulator of IL-1β Secretion
The generation of diversity and plasticity of transcriptional programs are key components of effective vertebrate immune responses. The role of Alternative Splicing has been recognized, but it is underappreciated and poorly understood as a critical mechanism for the regulation and fine-tuning of phy...
Autores principales: | Moura-Alves, Pedro, Neves-Costa, Ana, Raquel, Helena, Pacheco, Teresa Raquel, D'Almeida, Bruno, Rodrigues, Raquel, Cadima-Couto, Iris, Chora, Ângelo, Oliveira, Mariana, Gama-Carvalho, Margarida, Hacohen, Nir, Moita, Luis F. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096647/ https://www.ncbi.nlm.nih.gov/pubmed/21611201 http://dx.doi.org/10.1371/journal.pone.0019829 |
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