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Adenoma Formation following Limited Ablation of p120-Catenin in the Mouse Intestine
p120 loss destabilizes E-cadherin and could therefore result in tumor and/or metastasis-promoting activities similar to those caused by E-cadherin downregulation. Previously, we reported that p120 is essential in the intestine for barrier function, epithelial homeostasis and survival. Conditional p1...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096651/ https://www.ncbi.nlm.nih.gov/pubmed/21611205 http://dx.doi.org/10.1371/journal.pone.0019880 |