Cargando…

Adenoma Formation following Limited Ablation of p120-Catenin in the Mouse Intestine

p120 loss destabilizes E-cadherin and could therefore result in tumor and/or metastasis-promoting activities similar to those caused by E-cadherin downregulation. Previously, we reported that p120 is essential in the intestine for barrier function, epithelial homeostasis and survival. Conditional p1...

Descripción completa

Detalles Bibliográficos
Autores principales: Smalley-Freed, Whitney G., Efimov, Andrey, Short, Sarah P., Jia, Peilin, Zhao, Zhongming, Washington, M. Kay, Robine, Sylvie, Coffey, Robert J., Reynolds, Albert B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096651/
https://www.ncbi.nlm.nih.gov/pubmed/21611205
http://dx.doi.org/10.1371/journal.pone.0019880