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Characterization of the Metabolic Phenotype of Rapamycin-Treated CD8(+) T Cells with Augmented Ability to Generate Long-Lasting Memory Cells

BACKGROUND: Cellular metabolism plays a critical role in regulating T cell responses and the development of memory T cells with long-term protections. However, the metabolic phenotype of antigen-activated T cells that are responsible for the generation of long-lived memory cells has not been charact...

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Detalles Bibliográficos
Autores principales: He, Shan, Kato, Koji, Jiang, Jiu, Wahl, Daniel R., Mineishi, Shin, Fisher, Erin M., Murasko, Donna M., Glick, Gary D., Zhang, Yi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096660/
https://www.ncbi.nlm.nih.gov/pubmed/21611151
http://dx.doi.org/10.1371/journal.pone.0020107