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Characterization of the Metabolic Phenotype of Rapamycin-Treated CD8(+) T Cells with Augmented Ability to Generate Long-Lasting Memory Cells
BACKGROUND: Cellular metabolism plays a critical role in regulating T cell responses and the development of memory T cells with long-term protections. However, the metabolic phenotype of antigen-activated T cells that are responsible for the generation of long-lived memory cells has not been charact...
Autores principales: | He, Shan, Kato, Koji, Jiang, Jiu, Wahl, Daniel R., Mineishi, Shin, Fisher, Erin M., Murasko, Donna M., Glick, Gary D., Zhang, Yi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096660/ https://www.ncbi.nlm.nih.gov/pubmed/21611151 http://dx.doi.org/10.1371/journal.pone.0020107 |
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