Histone modification enhances the effectiveness of IL-13 receptor targeted immunotoxin in murine models of human pancreatic cancer

BACKGROUND: Interleukin-13 Receptor α2 (IL-13Rα2) is a tumor-associated antigen and target for cancer therapy. Since IL-13Rα2 is heterogeneously overexpressed in a variety of human cancers, it would be highly desirable to uniformly upregulate IL-13Rα2 expression in tumors for optimal targeting. METH...

Descripción completa

Detalles Bibliográficos
Autores principales: Fujisawa, Toshio, Joshi, Bharat H, Puri, Raj K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096924/
https://www.ncbi.nlm.nih.gov/pubmed/21477288
http://dx.doi.org/10.1186/1479-5876-9-37

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096924/
https://www.ncbi.nlm.nih.gov/pubmed/21477288
http://dx.doi.org/10.1186/1479-5876-9-37

Ejemplares similares