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The surprising negative correlation of gene length and optimal codon use - disentangling translational selection from GC-biased gene conversion in yeast

BACKGROUND: Surprisingly, in several multi-cellular eukaryotes optimal codon use correlates negatively with gene length. This contrasts with the expectation under selection for translational accuracy. While suggested explanations focus on variation in strength and efficiency of translational selecti...

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Detalles Bibliográficos
Autor principal: Stoletzki, Nina
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096941/
https://www.ncbi.nlm.nih.gov/pubmed/21481245
http://dx.doi.org/10.1186/1471-2148-11-93