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The surprising negative correlation of gene length and optimal codon use - disentangling translational selection from GC-biased gene conversion in yeast
BACKGROUND: Surprisingly, in several multi-cellular eukaryotes optimal codon use correlates negatively with gene length. This contrasts with the expectation under selection for translational accuracy. While suggested explanations focus on variation in strength and efficiency of translational selecti...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096941/ https://www.ncbi.nlm.nih.gov/pubmed/21481245 http://dx.doi.org/10.1186/1471-2148-11-93 |