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Akt is required for Stat5 activation and mammary differentiation

INTRODUCTION: The Akt pathway plays a central role in regulating cell survival, proliferation and metabolism, and is one of the most commonly activated pathways in human cancer. A role for Akt in epithelial differentiation, however, has not been established. We previously reported that mice lacking...

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Detalles Bibliográficos
Autores principales: Chen, Chien-Chung, Boxer, Robert B, Stairs, Douglas B, Portocarrero, Carla P, Horton, Rachel H, Alvarez, James V, Birnbaum, Morris J, Chodosh, Lewis A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096959/
https://www.ncbi.nlm.nih.gov/pubmed/20849614
http://dx.doi.org/10.1186/bcr2640