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Akt is required for Stat5 activation and mammary differentiation
INTRODUCTION: The Akt pathway plays a central role in regulating cell survival, proliferation and metabolism, and is one of the most commonly activated pathways in human cancer. A role for Akt in epithelial differentiation, however, has not been established. We previously reported that mice lacking...
Autores principales: | Chen, Chien-Chung, Boxer, Robert B, Stairs, Douglas B, Portocarrero, Carla P, Horton, Rachel H, Alvarez, James V, Birnbaum, Morris J, Chodosh, Lewis A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096959/ https://www.ncbi.nlm.nih.gov/pubmed/20849614 http://dx.doi.org/10.1186/bcr2640 |
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