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RARα1 control of mammary gland ductal morphogenesis and wnt1-tumorigenesis

INTRODUCTION: Retinoic acid signaling pathways are disabled in human breast cancer suggesting a controlling role in normal mammary growth that might be lost in tumorigenesis. We tested a single receptor isotype, RARα1 (retinoic acid receptor isotype alpha, isoform 1), for its role in mouse mammary g...

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Detalles Bibliográficos
Autores principales: Cohn, Ellen, Ossowski, Liliana, Bertran, Silvina, Marzan, Christine, Farias, Eduardo F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096972/
https://www.ncbi.nlm.nih.gov/pubmed/20923554
http://dx.doi.org/10.1186/bcr2724