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Antisense oligodeoxynucleotides targeting ATM strengthen apoptosis of laryngeal squamous cell carcinoma grown in nude mice

BACKGROUND: To conserve laryngeal function and elevate living quality of laryngeal squamous cell carcinoma (LSCC) patients, we designed antisense oligodeoxynucleotides (AS-ODNs) to reduce expression of ATM and to enhance the apoptosis of hep-2 (Human epidermoid laryngeal carcinoma) cells to radiatio...

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Detalles Bibliográficos
Autores principales: Feng, Jun, Zou, Jian, Li, Li, Zhao, Yongsheng, Liu, Shixi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097000/
https://www.ncbi.nlm.nih.gov/pubmed/21496344
http://dx.doi.org/10.1186/1756-9966-30-43