Safety and efficacy of the immunosuppressive agent 6-tioguanine in murine model of acute and chronic colitis

BACKGROUND: Oral thiopurines are effective and widely used in treatment of inflammatory bowel disease (IBD) in humans, although their use is limited due the development of adverse events. Here, we examine the efficacy and toxicity of oral treatment with 6-tioguanine (6-TG) and azathioprine (AZA) in...

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Detalles Bibliográficos
Autores principales: Kverka, Miloslav, Rossmann, Pavel, Tlaskalova-Hogenova, Helena, Klimesova, Klara, Jharap, Bindia, de Boer, Nanne K, Vos, Rene M, van Bodegraven, Adriaan A, Lukas, Milan, Mulder, Chris J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097145/
https://www.ncbi.nlm.nih.gov/pubmed/21545711
http://dx.doi.org/10.1186/1471-230X-11-47

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097145/
https://www.ncbi.nlm.nih.gov/pubmed/21545711
http://dx.doi.org/10.1186/1471-230X-11-47

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