Altering the Ad5 Packaging Domain Affects the Maturation of the Ad Particles

We have previously described a new family of mutant adenoviruses carrying different combinations of attB/attP sequences from bacteriophage PhiC31 flanking the Ad5 packaging domain. These novel helper viruses have a significantly delayed viral life cycle and a severe packaging impairment, regardless...

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Detalles Bibliográficos
Autores principales: Alba, Raul, Cots, Dan, Ostapchuk, Philomena, Bosch, Assumpcio, Hearing, Patrick, Chillon, Miguel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097180/
https://www.ncbi.nlm.nih.gov/pubmed/21611162
http://dx.doi.org/10.1371/journal.pone.0019564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097180/
https://www.ncbi.nlm.nih.gov/pubmed/21611162
http://dx.doi.org/10.1371/journal.pone.0019564

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