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Establishment of a Transgenic Mouse Model Specifically Expressing Human Serum Amyloid A in Adipose Tissue

Obesity and obesity co-morbidities are associated with a low grade inflammation and elevated serum levels of acute phase proteins, including serum amyloid A (SAA). In the non-acute phase in humans, adipocytes are major producers of SAA but the function of adipocyte-derived SAA is unknown. To clarify...

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Detalles Bibliográficos
Autores principales: Olsson, Maja, Ahlin, Sofie, Olsson, Bob, Svensson, Per-Arne, Ståhlman, Marcus, Borén, Jan, Carlsson, Lena M. S., Sjöholm, Kajsa
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097194/
https://www.ncbi.nlm.nih.gov/pubmed/21611116
http://dx.doi.org/10.1371/journal.pone.0019609