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Identification of Small-Molecule Inhibitors of Yersinia pestis Type III Secretion System YscN ATPase
Yersinia pestis is a Gram negative zoonotic pathogen responsible for causing bubonic and pneumonic plague in humans. The pathogen uses a type III secretion system (T3SS) to deliver virulence factors directly from bacterium into host mammalian cells. The system contains a single ATPase, YscN, necessa...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097197/ https://www.ncbi.nlm.nih.gov/pubmed/21611119 http://dx.doi.org/10.1371/journal.pone.0019716 |