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Vaginally Administered PEGylated LIF Antagonist Blocked Embryo Implantation and Eliminated Non-Target Effects on Bone in Mice

Female-controlled contraception/HIV prevention is critical to address health issues associated with gender inequality. Therefore, a contraceptive which can be administered in tandem with a microbicide to inhibit sexually transmitted infections, is desirable. Uterine leukemia inhibitory factor (LIF)...

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Detalles Bibliográficos
Autores principales: Menkhorst, Ellen, Zhang, Jian-Guo, Sims, Natalie A., Morgan, Phillip O., Soo, Priscilla, Poulton, Ingrid J., Metcalf, Donald, Alexandrou, Estella, Gresle, Melissa, Salamonsen, Lois A., Butzkueven, Helmut, Nicola, Nicos A., Dimitriadis, Evdokia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097203/
https://www.ncbi.nlm.nih.gov/pubmed/21611124
http://dx.doi.org/10.1371/journal.pone.0019665