Adenovirus Type 5 Induces Vitamin A–Metabolizing Enzymes in Dendritic Cells and Enhances Priming of Gut Homing CD8 T Cells

Protective immunity at the gut-associated mucosal tissue is induced primarily by oral/rectal immunization owing to the need for targeting antigen to the gut-resident dendritic cells (DC). Here we show that an adenovirus type 5 (Ad5) based HIV-1 vaccine can prime a durable antigen-specific CD8 T cell...

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Detalles Bibliográficos
Autores principales: Ganguly, Sumita, Manicassamy, Santhakumar, Amara, Rama Rao
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097311/
https://www.ncbi.nlm.nih.gov/pubmed/21289616
http://dx.doi.org/10.1038/mi.2011.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097311/
https://www.ncbi.nlm.nih.gov/pubmed/21289616
http://dx.doi.org/10.1038/mi.2011.1

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