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Adenovirus Type 5 Induces Vitamin A–Metabolizing Enzymes in Dendritic Cells and Enhances Priming of Gut Homing CD8 T Cells
Protective immunity at the gut-associated mucosal tissue is induced primarily by oral/rectal immunization owing to the need for targeting antigen to the gut-resident dendritic cells (DC). Here we show that an adenovirus type 5 (Ad5) based HIV-1 vaccine can prime a durable antigen-specific CD8 T cell...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097311/ https://www.ncbi.nlm.nih.gov/pubmed/21289616 http://dx.doi.org/10.1038/mi.2011.1 |