Optimization of Forced Degradation Using Experimental Design and Development of a Stability-Indicating Liquid Chromatographic Assay Method for Rebamipide in Bulk and Tablet Dosage Form

A novel stability-indicating RP-HPLC assay method was developed and validated for quantitative determination of rebamipide in bulk and tablet dosage form. Rebamipide (drug and drug product) solutions were exposed to acid and alkali hydrolysis, thermal stress, oxidation by hydrogen peroxide and photo...

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Detalles Bibliográficos
Autores principales: Sonawane, Sandeep, Gide, Paraag
Formato: Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097498/
https://www.ncbi.nlm.nih.gov/pubmed/21617774
http://dx.doi.org/10.3797/scipharm.1011-06

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097498/
https://www.ncbi.nlm.nih.gov/pubmed/21617774
http://dx.doi.org/10.3797/scipharm.1011-06

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