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New Substituted Isocoumarins and Dihydroisocoumarins and their Cytotoxic Activities

New isocoumarins were prepared in an efficient way from 2-iodobenzoic acid derivatives and hept-1-yne in a Sonogashira reaction, followed by spontaneous cyclization. Catalytic hydrogenation gave the corresponding dihydroisocoumarins. A 4-chloroisocoumarin was prepared on an alternative pathway. Some...

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Detalles Bibliográficos
Autores principales: Hampl, Veronika, Wetzel, Isolde, Bracher, Franz, Krauss, Jürgen
Formato: Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097510/
https://www.ncbi.nlm.nih.gov/pubmed/21617770
http://dx.doi.org/10.3797/scipharm.1011-10