Cisplatin sensitivity of testis tumour cells is due to deficiency in interstrand-crosslink repair and low ERCC1-XPF expression

BACKGROUND: Cisplatin based chemotherapy cures over 80% of metastatic testicular germ cell tumours (TGCT). In contrast, almost all other solid cancers in adults are incurable once they have spread beyond the primary site. Cell lines derived from TGCTs are hypersensitive to cisplatin reflecting the c...

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Detalles Bibliográficos
Autores principales: Usanova, Svetlana, Piée-Staffa, Andrea, Sied, Ulrike, Thomale, Jürgen, Schneider, Astrid, Kaina, Bernd, Köberle, Beate
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098011/
https://www.ncbi.nlm.nih.gov/pubmed/20846399
http://dx.doi.org/10.1186/1476-4598-9-248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098011/
https://www.ncbi.nlm.nih.gov/pubmed/20846399
http://dx.doi.org/10.1186/1476-4598-9-248

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