Biomarker discovery in heterogeneous tissue samples -taking the in-silico deconfounding approach

BACKGROUND: For heterogeneous tissues, such as blood, measurements of gene expression are confounded by relative proportions of cell types involved. Conclusions have to rely on estimation of gene expression signals for homogeneous cell populations, e.g. by applying micro-dissection, fluorescence act...

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Detalles Bibliográficos
Autores principales: Repsilber, Dirk, Kern, Sabine, Telaar, Anna, Walzl, Gerhard, Black, Gillian F, Selbig, Joachim, Parida, Shreemanta K, Kaufmann, Stefan HE, Jacobsen, Marc
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098067/
https://www.ncbi.nlm.nih.gov/pubmed/20070912
http://dx.doi.org/10.1186/1471-2105-11-27

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098067/
https://www.ncbi.nlm.nih.gov/pubmed/20070912
http://dx.doi.org/10.1186/1471-2105-11-27

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