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Biomarker discovery in heterogeneous tissue samples -taking the in-silico deconfounding approach
BACKGROUND: For heterogeneous tissues, such as blood, measurements of gene expression are confounded by relative proportions of cell types involved. Conclusions have to rely on estimation of gene expression signals for homogeneous cell populations, e.g. by applying micro-dissection, fluorescence act...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098067/ https://www.ncbi.nlm.nih.gov/pubmed/20070912 http://dx.doi.org/10.1186/1471-2105-11-27 |