Using simple artificial intelligence methods for predicting amyloidogenesis in antibodies

BACKGROUND: All polypeptide backbones have the potential to form amyloid fibrils, which are associated with a number of degenerative disorders. However, the likelihood that amyloidosis would actually occur under physiological conditions depends largely on the amino acid composition of a protein. We...

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Detalles Bibliográficos
Autores principales: David, Maria Pamela C, Concepcion, Gisela P, Padlan, Eduardo A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098112/
https://www.ncbi.nlm.nih.gov/pubmed/20144194
http://dx.doi.org/10.1186/1471-2105-11-79

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098112/
https://www.ncbi.nlm.nih.gov/pubmed/20144194
http://dx.doi.org/10.1186/1471-2105-11-79

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