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Using simple artificial intelligence methods for predicting amyloidogenesis in antibodies
BACKGROUND: All polypeptide backbones have the potential to form amyloid fibrils, which are associated with a number of degenerative disorders. However, the likelihood that amyloidosis would actually occur under physiological conditions depends largely on the amino acid composition of a protein. We...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098112/ https://www.ncbi.nlm.nih.gov/pubmed/20144194 http://dx.doi.org/10.1186/1471-2105-11-79 |