Gα(16 )interacts with tetratricopeptide repeat 1 (TPR1) through its β3 region to activate Ras independently of phospholipase Cβ signaling

BACKGROUND: G protein-coupled receptors constitute the largest family of cell surface receptors in the mammalian genome. As the core of the G protein signal transduction machinery, the Gα subunits are required to interact with multiple partners. The GTP-bound active state of many Gα subunits can bin...

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Detalles Bibliográficos
Autores principales: Liu, Andrew MF, Lo, Rico KH, Guo, Emily X, Ho, Maurice KC, Ye, Richard D, Wong, Yung H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098143/
https://www.ncbi.nlm.nih.gov/pubmed/21486497
http://dx.doi.org/10.1186/1472-6807-11-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098143/
https://www.ncbi.nlm.nih.gov/pubmed/21486497
http://dx.doi.org/10.1186/1472-6807-11-17

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