HIV-1 integrase modulates the interaction of the HIV-1 cellular cofactor LEDGF/p75 with chromatin

BACKGROUND: Chromatin binding plays a central role in the molecular mechanism of LEDGF/p75 in HIV-1 DNA integration. Conflicting results have been reported in regards to the relevance of the LEDGF/p75 chromatin binding element PWWP domain in its HIV-1 cofactor activity. RESULTS: Here we present evid...

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Detalles Bibliográficos
Autores principales: Astiazaran, Paulina, Bueno, Murilo TD, Morales, Elisa, Kugelman, Jeffrey R, Garcia-Rivera, Jose A, Llano, Manuel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098157/
https://www.ncbi.nlm.nih.gov/pubmed/21510906
http://dx.doi.org/10.1186/1742-4690-8-27

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098157/
https://www.ncbi.nlm.nih.gov/pubmed/21510906
http://dx.doi.org/10.1186/1742-4690-8-27

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