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Highly frequent promoter methylation and PIK3CA amplification in non-small cell lung cancer (NSCLC)

BACKGROUND: Lung cancer is the leading cause of cancer-related death worldwide. Genetic and epigenetic alterations have been identified frequently in lung cancer, such as promoter methylation, gene mutations and genomic amplification. However, the interaction between genetic and epigenetic events an...

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Detalles Bibliográficos
Autores principales: Ji, Meiju, Guan, Haixia, Gao, Cuixia, Shi, Bingyin, Hou, Peng
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098185/
https://www.ncbi.nlm.nih.gov/pubmed/21507233
http://dx.doi.org/10.1186/1471-2407-11-147