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SIV Nef Proteins Recruit the AP-2 Complex to Antagonize Tetherin and Facilitate Virion Release

Lentiviral Nef proteins have multiple functions and are important for viral pathogenesis. Recently, Nef proteins from many simian immunodefiency viruses were shown to antagonize a cellular antiviral protein, named Tetherin, that blocks release of viral particles from the cell surface. However, the m...

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Detalles Bibliográficos
Autores principales: Zhang, Fengwen, Landford, Wilmina N., Ng, Melinda, McNatt, Matthew W., Bieniasz, Paul D., Hatziioannou, Theodora
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098198/
https://www.ncbi.nlm.nih.gov/pubmed/21625568
http://dx.doi.org/10.1371/journal.ppat.1002039