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Type I Interferon Production Induced by Streptococcus pyogenes-Derived Nucleic Acids Is Required for Host Protection

Streptococcus pyogenes is a Gram-positive human pathogen that is recognized by yet unknown pattern recognition receptors (PRRs). Engagement of these receptor molecules during infection with S. pyogenes, a largely extracellular bacterium with limited capacity for intracellular survival, causes innate...

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Detalles Bibliográficos
Autores principales: Gratz, Nina, Hartweger, Harald, Matt, Ulrich, Kratochvill, Franz, Janos, Marton, Sigel, Stefanie, Drobits, Barbara, Li, Xiao-Dong, Knapp, Sylvia, Kovarik, Pavel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098218/
https://www.ncbi.nlm.nih.gov/pubmed/21625574
http://dx.doi.org/10.1371/journal.ppat.1001345