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Transcriptional Activators of Human Genes with Programmable DNA-Specificity

TAL (transcription activator-like) effectors are translocated by Xanthomonas bacteria into plant cells where they activate transcription of target genes. DNA target sequence recognition occurs in a unique mode involving a central domain of tandem repeats. Each repeat recognizes a single base pair in...

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Detalles Bibliográficos
Autores principales: Geiβler, René, Scholze, Heidi, Hahn, Simone, Streubel, Jana, Bonas, Ulla, Behrens, Sven-Erik, Boch, Jens
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098229/
https://www.ncbi.nlm.nih.gov/pubmed/21625585
http://dx.doi.org/10.1371/journal.pone.0019509