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Dual Function of the NK Cell Receptor 2B4 (CD244) in the Regulation of HCV-Specific CD8+ T Cells

The outcome of viral infections is dependent on the function of CD8+ T cells which are tightly regulated by costimulatory molecules. The NK cell receptor 2B4 (CD244) is a transmembrane protein belonging to the Ig superfamily which can also be expressed by CD8+ T cells. The aim of this study was to a...

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Detalles Bibliográficos
Autores principales: Schlaphoff, Verena, Lunemann, Sebastian, Suneetha, Pothakamuri Venkata, Jaroszewicz, Jerzy, Grabowski, Jan, Dietz, Julia, Helfritz, Fabian, Bektas, Hueseyin, Sarrazin, Christoph, Manns, Michael Peter, Cornberg, Markus, Wedemeyer, Heiner
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098233/
https://www.ncbi.nlm.nih.gov/pubmed/21625589
http://dx.doi.org/10.1371/journal.ppat.1002045