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Expansion of CD4(+)CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt Cells in Allergic Inflammation, Local Lung Distribution and Chemokine Gene Expression

Allergic asthma is associated with airway eosinophilia, which is regulated by different T-effector cells. T cells express transcription factors T-bet, GATA-3, RORγt and Foxp3, representing Th1, Th2, Th17 and Treg cells respectively. No study has directly determined the relative presence of each of t...

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Detalles Bibliográficos
Autores principales: Lu, You, Malmhäll, Carina, Sjöstrand, Margareta, Rådinger, Madeleine, O'Neil, Serena E., Lötvall, Jan, Bossios, Apostolos
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098248/
https://www.ncbi.nlm.nih.gov/pubmed/21625544
http://dx.doi.org/10.1371/journal.pone.0019889