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Clinical Clostridium difficile: Clonality and Pathogenicity Locus Diversity

Clostridium difficile infection (CDI) is an important cause of mortality and morbidity in healthcare settings. The major virulence determinants are large clostridial toxins, toxin A (tcdA) and toxin B (tcdB), encoded within the pathogenicity locus (PaLoc). Isolates vary in pathogenicity from hypervi...

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Detalles Bibliográficos
Autores principales: Dingle, Kate E., Griffiths, David, Didelot, Xavier, Evans, Jessica, Vaughan, Alison, Kachrimanidou, Melina, Stoesser, Nicole, Jolley, Keith A., Golubchik, Tanya, Harding, Rosalind M., Peto, Tim E., Fawley, Warren, Walker, A. Sarah, Wilcox, Mark, Crook, Derrick W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098275/
https://www.ncbi.nlm.nih.gov/pubmed/21625511
http://dx.doi.org/10.1371/journal.pone.0019993