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Significance of Thymosin β4 and Implication of PINCH-1-ILK-α-Parvin (PIP) Complex in Human Dilated Cardiomyopathy

Myocardial remodeling is a major contributor in the development of heart failure (HF) after myocardial infarction (MI). Integrin-linked kinase (ILK), LIM-only adaptor PINCH-1, and α-parvin are essential components of focal adhesions (FAs), which are highly expressed in the heart. ILK binds tightly t...

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Detalles Bibliográficos
Autores principales: Sopko, Nikolai, Qin, Yilu, Finan, Amanda, Dadabayev, Alisher, Chigurupati, Sravanthi, Qin, Jun, Penn, Marc S., Gupta, Sudhiranjan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098280/
https://www.ncbi.nlm.nih.gov/pubmed/21625516
http://dx.doi.org/10.1371/journal.pone.0020184